Investigating B cell Biology and Autoantigens in Autoimmune and Neuroimmunological Diseases
Welcome to the Lanz Lab
Our research focuses on B cell biology in autoimmune and neuroimmunological diseases. We use high-throughput screening technologies and methods from structural and cell biology to identify new autoantigens and to understand how self-reactive B cells escape tolerance mechanisms. We are particularly interested in molecular mechanisms that explain the association between Epstein Barr Virus (EBV) and autoimmunity.
Lab News
October 2024
Warm welcome to Friederike Held, a neurologist and neuroimmunologist from Munich, Germany. We are excited to have her in our lab. Her postdoc project will focus on B cell biology in MS and screening antibody responses with large protein libraries.
August 2024
We are very happy to welcome Tahj to the lab. He is part of the Stanford REACH postbac program and will work on generating yeast display libraries and characterizing anti-EBV antibody responses in autoimmune diseases.
August 2024
We are very excited to welcome Frederik from Berlin, Germany. He is a neurologist and neuroimmunologist with years of clinical and research experience in the field of MS and neuroinflammation, and will pursue a research postdoc in our lab. He will study how the Epstein-Barr virus contributes to MS pathogenesis.
July 2024
Max is the lab’s first student, who joins us for a 2-month internship within the SIMR program. His project is designing a new Yeast Display Library. Welcome Max!
May 2024
Congratulations Neda for receiving a NIH K23! Well deserved!
March 2024
Together with Mark Davis, Tobi organizes the Stanford Autoimmune and Allergy Supergroup Conference with two days of scientific talks pertaining to autoimmunity, bringing together researchers and clinicians from all fields of Medicine. With several invited speakers and a keynote from Prof. Georg Schett, the event drew an audience of approximately 270 people.
December 2023
Congratulations Alison for receiving the School of Medicine Dean’s Postdoctoral Fellowship! Most awesome.
September 2023
Welcome Saurabh, who just defended his PhD in immunology and will do his postdoc in the lanz lab. He plans to generate and analyze single-cell sequencing data and other large next-gen. datasets from IgG4-related disease, ANCA-vasculitis, MS, and other autoimmune disorders.
September 2023
We are thrilled that Tilini starts her postdoc in the Robinson lab, co-mentored by Tobi. She and Alison were already a team before they came to Stanford, having received their PhDs in the same protein biochemistry lab. Tilini will use structural biology and cell biology methods to elucidate pathological anti-EBV antibody responses in patients with SLE and MS.
August 2023
We are very excited that Aleko joins our lab. He will express antibodies and other proteins and solve their structures with X-ray crystallography.
August 2023
Welcome Alison, the Lanz Lab’s first PhD postdoc! With a ton of experience in protein science and structural biology, she will solve the structure of a major MS antigen and develop a novel antigen-specific therapy.
July 2023
The last centrifuges arrive. The lab is ready for great discoveries.
>>>
>>>
June 2023
New Hoods, new incubators, new centrifuges, and a new microscope for our TC!
>>>
>>>
May 2023
A lot of things to renovate, buy, and build.
Our yeast display space is finally ready to go.
>>>
>>>
March 2023
The Lanz lab receives major funding for MS research from the
Department of Defense.
March 2023
Neda is a clinical neuroimmunologist and a joint postdoctoral fellow in the Robinson and Lanz labs. In a collaborative project with researchers from the Karolinska Institute in Sweden, she will conduct large bead-based protein arrays to understand antibody responses against EBV and mimicking self antigens in MS patients vs. healthy individuals.
March 2023
Welcome Lab Manager Heidi to the Lanz Lab! There is a lot of work ahead of us…
March 2023
The Lanz Lab opens its doors at Stanford.